A novel linkage-disequilibrium corrected genomic relationship matrix for SNP-heritability estimation and genomic prediction
نویسندگان
چکیده
منابع مشابه
Accurate Estimation of Effective Population Size in the Korean Dairy Cattle Based on Linkage Disequilibrium Corrected by Genomic Relationship Matrix
Linkage disequilibrium between markers or genetic variants underlying interesting traits affects many genomic methodologies. In many genomic methodologies, the effective population size (Ne) is important to assess the genetic diversity of animal populations. In this study, dairy cattle were genotyped using the Illumina BovineHD Genotyping BeadChips for over 777,000 SNPs located across all autos...
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The aim of this study was to determine the effect of marker density, level of heritability, number of QTLs, and size of training set on the genomic accuracy over three generations. Thereby, a trait was simulated with heritability of 0.10, 0.25 or 0.40. For each animal, a genome with 20 chromosomes, 1 Morgan each, was simulated. Different marker densities (2000, 4000 and 6000 markers) and 400 an...
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متن کاملAccuracy of Genomic Prediction in Switchgrass (Panicum virgatum L.) Improved by Accounting for Linkage Disequilibrium.
Switchgrass is a relatively high-yielding and environmentally sustainable biomass crop, but further genetic gains in biomass yield must be achieved to make it an economically viable bioenergy feedstock. Genomic selection (GS) is an attractive technology to generate rapid genetic gains in switchgrass, and meet the goals of a substantial displacement of petroleum use with biofuels in the near fut...
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ژورنال
عنوان ژورنال: Heredity
سال: 2017
ISSN: 0018-067X,1365-2540
DOI: 10.1038/s41437-017-0023-4